MR1 anticorps

N° du produit ABIN2665278

Détail du produit anti-MR1 anticorps

Antigène: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MR1 est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Réactivité croisée: Boeuf (Vache)

Aucune reactivité croisée: Souris

Purification: The antibody was purified by affinity chromatography.

Clone: 26-5

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur MR1

Antigène: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Autre désignation: MR1 (MR1 Produits)

Synonymes: anticorps YFV, anticorps hlals, anticorps MGC154362, anticorps MR1, anticorps DKFZp468C1823, anticorps HLALS, anticorps H2ls, anticorps Hlals, anticorps MHC class I antigen YF5, anticorps major histocompatibility complex, class I-related, anticorps major histocompatibility complex, class I-related L homeolog, anticorps YF5, anticorps MR1, anticorps mr1.L, anticorps mr1, anticorps Mr1

Sujet: MHC-related protein 1, also known as MR1, is a nonclassical MHC class I molecule highly conserved in mammals, particularly in its α1/α2 domains. MR1 is required for the development and expansion of the mucosal-associated invariant T (MAIT) cells. The transcripts for MR1 are ubiquitously expressed, but its expression on the cell surface seems to be ligand-dependent. MR1 is involved in the presentation of vitamin-derived compounds from bacterial biosynthetic pathways.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints