SPHK1 anticorps

N° du produit ABIN2665362

Cet anticorps Souris Monoclonal détecte spécifiquement SPHK1 dans FACS. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour SPHK1 anticorps (ABIN2665362)

Antigène: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SPHK1 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: 1A5SC

Détail du produit anti-SPHK1 anticorps

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur SPHK1

Antigène: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Autre désignation: SPHK1

Sujet: SPHK1 is a lipid kinase that catalyzes the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P) which is a key sphingolipid signaling molecule involved in cell growth, survival, differentiation, and motility. As an important regulator of ceramide, sphingosine, and S1P, SPHK1 plays important roles in immunological, inflammatory diseases, and cancer. SPHK1 is overexpressed in various types of cancers, and upregulation of SPHK1 has been associated with tumor angiogenesis and resistance to radiation and chemotherapy. Agents targeting the SPHK1 have the potential as therapeutics for cancer, immunological, and inflammatory disorders.

Pathways: VEGF Signaling