DDIT3 anticorps

N° du produit ABIN2668558

Il existe 2+ publications pour ce produit. L’anticorps anti-DDIT3 Monoclonal Souris est utilisé pour la détection de DDIT3 dans des échantillons de Souris. Il a été validé pour WB et IP.

Aperçu rapide pour DDIT3 anticorps (ABIN2668558)

Antigène: DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DDIT3 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: 9C8

Détail du produit anti-DDIT3 anticorps

Fonction: Ddit3 antibody (mAb) (Clone 9C8)

Purification: Protein G Chromatography

Immunogène: This antibody was raised against full-length recombinant mouse Ddit3 protein.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-DDIT3 (ABIN2668558)

Kuroda, Wang, Sok, Yin, Chung, Giannotti, Jacobs, Fitz, Murtha-Riel, Turner, Ron: "Induction of a secreted protein by the myxoid liposarcoma oncogene." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 9, pp. 5025-30, (1999) (PubMed).

Wang, Kuroda, Sok, Batchvarova, Kimmel, Chung, Zinszner, Ron: "Identification of novel stress-induced genes downstream of chop." dans: The EMBO journal, Vol. 17, Issue 13, pp. 3619-30, (1998) (PubMed).

Détails sur DDIT3

Antigène: DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

Autre désignation: Ddit3

Sujet: Ddit3 (DNA-damage-inducible transcript 3, CHOP) is a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis.

Poids moléculaire: 29 kDa

ID gène: 13198

NCBI Accession: NP_031863

Pathways: Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis