ITGB1 anticorps

N° du produit ABIN2689155

L’anticorps Rat Monoclonal anti-ITGB1 a été validé pour WB, FACS, ELISA, IP et Func. Il convient pour détecter ITGB1 dans des échantillons de Humain. Il y a 4+ publications disponibles.

Aperçu rapide pour ITGB1 anticorps (ABIN2689155)

Antigène: ITGB1 (Integrin beta 1 (ITGB1))

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGB1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP), Functional Studies (Func)

Clone: Mab 13

Détail du produit anti-ITGB1 anticorps

Marque: BD Pharmingen™

Attributs du produit: The Mab 13 monoclonal antibody specifically binds to CD29. CD29 is a 130 kDa integrin β1 subunit that is expressed as a heterodimeric complex with one of six distinct α subunits, comprising the very late activation antigen (VLA) subfamily of adhesion receptors. The family of β1 integrins includes receptors for vascular cell adhesion molecule 1 (VCAM-1), extracellular matrix (ECM) components such as collagen (COL), fibronectin (FN), laminin (LM) and vitronectin (VN), and pathogens. The β1 subunit is widely expressed by T and B cells, dendritic cells, NK cells, monocytes and macrophages, granulocytes, platelets, endothelial and epithelial cells, and stem cells. Flow cytometric analysis of CD29 expression on human peripheral blood lymphocytes. Whole blood was stained with Purified Rat Anti-Human CD29 antibody (Cat. No. 552828, solid line histogram) or with Purified Rat IgG2a, κ Isotype Control (Cat. No. 553927/555841, dashed line histogram), followed by FITC Goat Anti-Rat Ig (Cat. No 554016). Erythrocytes were lysed with BD Pharm Lyse™ Lysing Buffer (Cat. No. 555899). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.

BD Pharmingen™ Purified Rat Anti-Human CD29 - Purified - Clone Mab 13 - Isotype Rat IgG2a, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Purified Fibronectin Receptor from Human Placenta

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-ITGB1 (ABIN2689155)

Bohnsack: "CD11/CD18-independent neutrophil adherence to laminin is mediated by the integrin VLA-6." dans: Blood, Vol. 79, Issue 6, pp. 1545-52, (1992) (PubMed).

Chan, Elices, Murphy, Hemler: "Adhesion to vascular cell adhesion molecule 1 and fibronectin. Comparison of alpha 4 beta 1 (VLA-4) and alpha 4 beta 7 on the human B cell line JY." dans: The Journal of biological chemistry, Vol. 267, Issue 12, pp. 8366-70, (1992) (PubMed).

Hertle, Adams, Watt: "Integrin expression during human epidermal development in vivo and in vitro." dans: Development (Cambridge, England), Vol. 112, Issue 1, pp. 193-206, (1992) (PubMed).

Teixidó, Hemler, Greenberger, Anklesaria: "Role of beta 1 and beta 2 integrins in the adhesion of human CD34hi stem cells to bone marrow stroma." dans: The Journal of clinical investigation, Vol. 90, Issue 2, pp. 358-67, (1992) (PubMed).

Détails sur ITGB1

Antigène: ITGB1 (Integrin beta 1 (ITGB1))

Autre désignation: CD29

Sujet: Synonyms: ITGB1, Integrin beta-1, Integrin β1, FNRB, GPIIA, ITB1, MDF2, MSK12, VLA-4β

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome