ITGB1 anticorps

N° du produit ABIN2689157

Cet anticorps Hamster arménien Monoclonal détecte spécifiquement ITGB1 dans FACS, IHC (fro) et IHC (f). Il présente une réactivité envers Souris et Rat et a été mentionné dans 2+ publications.

Aperçu rapide pour ITGB1 anticorps (ABIN2689157)

Antigène: ITGB1 (Integrin beta 1 (ITGB1))

Reactivité: Souris, Rat

Hôte: Hamster arménien

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGB1 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: HM beta1

Détail du produit anti-ITGB1 anticorps

Marque: BD Pharmingen™

Attributs du produit: The HM β1-1 monoclonal antibody specifically binds to the 130- kDa integrin β1 chain (CD29). CD29 is expressed on the cell surface as a heterodimer with one of the distinct integrin-α chains. With α1 through α6 (CD49a through CD49f), it forms the VLA-1 through VLA-6 complexes, respectively, and with αv (CD51), it forms αvβ1 integrin. It also associates with the integrin α7 α8, and α9 chains in non-lymphoid tissues. As a result, CD29 has a broad tissue distribution, including lymphocytes, endothelia, smooth muscle, epithelia, and oocytes. This hamster mAb to a mouse leukocyte antigen has been observed to crossreact with similar populations of rat leukocytes. Source of the immunogen was purified mouse VLA-4 (α4β1, CD49d/CD29). Immunohistochemical staining of CD29 positive cells. Frozen sections of normal mouse spleen were stained with Purified Hamster Anti-Mouse CD29 (Cat. No. 550530) antibody. Endothelial cells of the central arteriole and splenic sinuses can be identified by the brown labeling of their cell membranes. Amplification 20X.

BD Pharmingen™ Purified Hamster Anti-Mouse CD29 - Purified - Clone HM β1-1 - Isotype Armenian Hamster IgG2, λ1 - Reactivity Ms, Rat - 1 mL

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Purified mouse VLA-4

Isotype: IgG2 lambda

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 15.625 μg/mL

Buffer: Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-ITGB1 (ABIN2689157)

Noto, Kato, Okumura, Yagita: "Identification and functional characterization of mouse CD29 with a mAb." dans: International immunology, Vol. 7, Issue 5, pp. 835-42, (1995) (PubMed).

Springer: "Adhesion receptors of the immune system." dans: Nature, Vol. 346, Issue 6283, pp. 425-34, (1990) (PubMed).

Détails sur ITGB1

Antigène: ITGB1 (Integrin beta 1 (ITGB1))

Autre désignation: CD29

Sujet: Synonyms: Itgb1, Integrin beta-1, Fnrb, gpIIa, VLA-4 subunit beta

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome