CD42a anticorps

N° du produit ABIN2689252

Détail du produit anti-CD42a anticorps

Antigène: CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD42a est non-conjugé

Application: Flow Cytometry (FACS)

Marque: BD Pharmingen™

Attributs du produit: Reacts with a 17-22kD, single chain integral membrane glycoprotein, also known as GPIX. CD42a forms a noncovalently linked complex (GPIb/GPIX/GPV) with CD42b, CD42c and CD42d. It is expressed on platelets and megakaryocytes and is absent on the platelets of patients with Bernadr-Soulier Syndrome (BSS). Although the CD42a function is not fully understood, GPIX glycoprotein is important for the assembly and membrane expression of the complex and for the maintenance of the functional conformation of CD42b (GPIb). Profile of resting platelets analyzed by flow cytometry

BD Pharmingen™ Purified Mouse Anti-Human CD42a - Purified - Clone ALMA.16 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: ALMA-16

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-CD42a (ABIN2689252)

Schick, Walker: "The acylation of megakaryocyte proteins: glycoprotein IX is primarily myristoylated while glycoprotein Ib is palmitoylated." dans: Blood, Vol. 87, Issue 4, pp. 1377-84, (1996) (PubMed).

Hickey, Williams, Roth: "Human platelet glycoprotein IX: an adhesive prototype of leucine-rich glycoproteins with flank-center-flank structures." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 17, pp. 6773-7, (1989) (PubMed).

Fox, Aggerbeck, Berndt: "Structure of the glycoprotein Ib.IX complex from platelet membranes." dans: The Journal of biological chemistry, Vol. 263, Issue 10, pp. 4882-90, (1988) (PubMed).

Détails sur CD42a

Antigène: CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

Autre désignation: CD42a (GP9 Produits)

Synonymes: anticorps cd42a, anticorps gpix, anticorps GP9, anticorps GPIX, anticorps Cd42, anticorps CD42a, anticorps glycoprotein IX platelet, anticorps glycoprotein IX platelet L homeolog, anticorps glycoprotein IX (platelet), anticorps glycoprotein 9 (platelet), anticorps GP9, anticorps gp9.L, anticorps Gp9