ITGA5 anticorps (Biotin)

N° du produit ABIN2689318

Détail du produit anti-ITGA5 anticorps (Biotin)

Antigène: ITGA5 (Integrin, alpha 5 (ITGA5))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGA5 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Marque: BD Pharmingen™

Attributs du produit: The 5H10-27 (MFR5) antibody reacts with the α5 chain of the integrin α5β1 fibronectin receptor (CD49e/CD29, VLA-5) on thymocytes, activated T lymphocytes, mast cells, and a variety of mouse cell lines, but not splenocytes. Soluble 5H10-27 (MFR5) antibody has been reported to inhibit VLA-5-mediated functions in vitro. In addition, immobilized mAb 5H10-27 (MFR5) has been demonstrated to costimulate the proliferative response of CD8+ T cells to plate-bound anti-CD3e antibody. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.

BD Pharmingen™ Biotin Rat Anti-Mouse CD49e - Biotin - Clone 5H10-27 (MFR5) - Isotype Rat IgG2a, κ - Reactivity Ms - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Mouse mast cell line MC/9

Clone: 5H10

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Références pour anticorps anti-ITGA5 (Biotin) (ABIN2689318)

Cukierman, Pankov, Stevens, Yamada: "Taking cell-matrix adhesions to the third dimension." dans: Science (New York, N.Y.), Vol. 294, Issue 5547, pp. 1708-12, (2001) (PubMed).

Rich, Van Nood, Lee: "Role of alpha 5 beta 1 integrin in TGF-beta 1-costimulated CD8+ T cell growth and apoptosis." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 7, pp. 2916-23, (1996) (PubMed).

Ruppert, Aigner, Hubbe, Yagita, Altevogt: "The L1 adhesion molecule is a cellular ligand for VLA-5." dans: The Journal of cell biology, Vol. 131, Issue 6 Pt 2, pp. 1881-91, (1996) (PubMed).

Halvorson, Coligan: "Enhancement of VLA integrin receptor function on thymocytes by cAMP is dependent on the maturation stage of the thymocytes." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 10, pp. 4567-74, (1995) (PubMed).

Hardy, Minguell: "Modulation of the adhesion of hemopoietic progenitor cells to the RGD site of fibronectin by interleukin 3." dans: Journal of cellular physiology, Vol. 164, Issue 2, pp. 315-23, (1995) (PubMed).

Kinashi, Springer: "Adhesion molecules in hematopoietic cells." dans: Blood cells, Vol. 20, Issue 1, pp. 25-44, (1995) (PubMed).

Détails sur ITGA5

Antigène: ITGA5 (Integrin, alpha 5 (ITGA5))

Autre désignation: CD49e (ITGA5 Produits)

Synonymes: anticorps ITGA5, anticorps Cd49e, anticorps Fnra, anticorps VLA5, anticorps CD49e, anticorps FNRA, anticorps VLA5A, anticorps Itga5_retired, anticorps integrin subunit alpha 5, anticorps integrin alpha 5 (fibronectin receptor alpha), anticorps ITGA5, anticorps Itga5

Sujet: Synonyms: Integrin α5 chain

Pathways: Integrin Complex