C5AR1 anticorps

N° du produit ABIN2689429

Cet anticorps anti-C5AR1 est un anticorps Souris Monoclonal détectant C5AR1 dans FACS et IF. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour C5AR1 anticorps (ABIN2689429)

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp C5AR1 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: D53

Détail du produit anti-C5AR1 anticorps

Marque: BD Pharmingen™

Attributs du produit: Reacts with a 40 kDa polypeptide expressed on granulocytes, monocytes and macrophages. CD88 is a G type protein-coupled receptor with seven transmembrane domains. It binds to C5a, the α chain of the complement component C5. C5a is cleaved from C5 during complement activation. The binding of C5a to C5a receptor (C5aR, CD88) on granulocytes leads to various effects including shedding of selectins, upregulation of adhesion molecules, chemotaxis, granule exocytosis and activation of NADPH oxidase.

BD Pharmingen™ Purified Mouse Anti-Human CD88 - Purified - Clone D53-1473 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-C5AR1 (ABIN2689429)

Morelli, Larregina, Chuluyán, Kolkowski, Fainboim: "Expression and modulation of C5a receptor (CD88) on skin dendritic cells. Chemotactic effect of C5a on skin migratory dendritic cells." dans: Immunology, Vol. 89, Issue 1, pp. 126-34, (1996) (PubMed).

Détails sur C5AR1

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Autre désignation: CD88

Sujet: Synonyms: C5a Receptor

Pathways: Système du Complément