C5AR1 anticorps (AA 15-27) (APC)

N° du produit ABIN7505962

Détail du produit anti-C5AR1 anticorps (APC)

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Épitope: AA 15-27

Reactivité: Humain, Boeuf (Vache), Lapin, Furet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp C5AR1 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Fonction: Anti-Hu CD88 APC

Specificité: The mouse monoclonal antibody S5/1 recognizes an extracellular epitope of CD88 protein, a 43 kDa receptor of C5a component of the complement cascade.

Purification: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: Recombinant N-terminal peptide (Asp15-Asp27) of human C5aR

Clone: S5-1

Isotype: IgG2a kappa

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Stockage

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur C5AR1

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Autre désignation: CD88 (C5AR1 Produits)

Synonymes: anticorps C5A, anticorps C5AR, anticorps C5R1, anticorps CD88, anticorps C5aR, anticorps C5r1, anticorps Cd88, anticorps D7Msu1, anticorps GPR77, anticorps complement C5a receptor 1, anticorps complement component 5a receptor 1, anticorps C5AR1, anticorps C5ar1, anticorps c5ar1

Sujet: Complement C5a receptor 1,CD88 / C5aR is a G protein-coupled seven membrane-spanning protein serving as a receptor for C5a component of the complement cascade, and is expressed mainly by monocytes, macrophages, neutrophils, eosinophils, and mast cells, but also e.g. by hepatocytes, glial cells, vascular endothelial cells, or cardiomyocytes. The binding of C5a to CD88 is associated with inflammatory response, including superoxide anion production, chemotaxis, and increased production of acute phase proteins. Expression of CD88 on synovial mast cells and their C5a-mediated degranulation plays a role in pathogenesis of rheumatoid arthritis.,C5A, C5R1, C5AR1

ID gène: 728

UniProt: P21730

Pathways: Système du Complément