IL12 anticorps (Biotin)

N° du produit ABIN2689728

Il existe 3+ publications pour ce produit. L’anticorps anti-IL12 Monoclonal Rat est utilisé pour la détection de IL12 dans des échantillons de Souris. Il a été validé pour ELISA, WB et IP.

Aperçu rapide pour IL12 anticorps (Biotin) (ABIN2689728)

Antigène: IL12 (Interleukin 12 (IL12))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL12 est conjugé à/à la Biotin

Application: ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Clone: C17-8

Détail du produit anti-IL12 anticorps (Biotin)

Attributs du produit: The C17.8 antibody reacts with the free p40 monomer of IL-12 as well as the p40 subunit complexed as homodimer or complexed with p35 as a p70 heterodimer.

BD Pharmingen™ Biotin Rat Anti-Mouse IL-12 (p40/p70) - Biotin - Clone C17.8 - Isotype Rat IgG2a - Reactivity Ms - 0.5 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Recombinant Mouse IL-12 p70

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Références pour anticorps anti-IL12 (Biotin) (ABIN2689728)

Neurath, Fuss, Kelsall, Stüber, Strober: "Antibodies to interleukin 12 abrogate established experimental colitis in mice." dans: The Journal of experimental medicine, Vol. 182, Issue 5, pp. 1281-90, (1995) (PubMed).

Wysocka, Kubin, Vieira, Ozmen, Garotta, Scott, Trinchieri: "Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice." dans: European journal of immunology, Vol. 25, Issue 3, pp. 672-6, (1995) (PubMed).

DAndrea, Rengaraju, Valiante, Chehimi, Kubin, Aste, Chan, Kobayashi, Young, Nickbarg: "Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells." dans: The Journal of experimental medicine, Vol. 176, Issue 5, pp. 1387-98, (1992) (PubMed).

Détails sur IL12

Antigène: IL12 (Interleukin 12 (IL12))

Autre désignation: IL-12 p40,p70

Pathways: Signalistation JAK/STAT, Signalisation TLR, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome