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IL12 anticorps

IL12 Reactivité: Souris ELISA Hôte: Rat Monoclonal C15-6 unconjugated
N° du produit ABIN2689730
  • Antigène Voir toutes IL12 Anticorps
    IL12 (Interleukin 12 (IL12))
    Reactivité
    • 52
    • 23
    • 16
    • 7
    • 4
    • 2
    • 1
    • 1
    Souris
    Hôte
    • 32
    • 30
    • 17
    • 15
    • 2
    Rat
    Clonalité
    • 47
    • 45
    Monoclonal
    Conjugué
    • 44
    • 16
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp IL12 est non-conjugé
    Application
    • 71
    • 59
    • 26
    • 26
    • 16
    • 12
    • 11
    • 9
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    Marque
    BD Pharmingen™
    Attributs du produit
    The C15.6 antibody reacts with both free and complexed (homodimer p80 and heterodimer p70) forms of the p40 subunit of mouse interleukin-12 (IL-12). The immunogen used to generate the C15.6 hybridoma was recombinant mouse IL-12 p70 protein. p40 has also been described as a subunit of IL-23 and thus it is possible that the C15.6 antibody will crossreact with IL-23. This antibody is routinely tested by ELISA capture. Other applications were tested during antibody development only or reported in the literature. Mouse IL-12p40 standard curve.

    BD Pharmingen™ Purified Rat Anti-Mouse IL-12 p40/p70 - Purified - Clone C15.6 - Isotype Rat IgG1 - Reactivity Ms - 1 mg
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogène
    CHO-expressed recombinant mouse IL-12 p70 protein
    Clone
    C15-6
    Isotype
    IgG1
    Top Product
    Discover our top product IL12 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store undiluted at 4°C.
  • Oppmann, Lesley, Blom, Timans, Xu, Hunte, Vega, Yu, Wang, Singh, Zonin, Vaisberg, Churakova, Liu, Gorman, Wagner, Zurawski, Liu, Abrams, Moore, Rennick, de Waal-Malefyt, Hannum, Bazan, Kastelein: "Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12." dans: Immunity, Vol. 13, Issue 5, pp. 715-25, (2001) (PubMed).

    Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." dans: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).

    Wysocka, Kubin, Vieira, Ozmen, Garotta, Scott, Trinchieri: "Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice." dans: European journal of immunology, Vol. 25, Issue 3, pp. 672-6, (1995) (PubMed).

  • Antigène
    IL12 (Interleukin 12 (IL12))
    Autre désignation
    IL-12 p40,p70 (IL12 Produits)
    Synonymes
    anticorps CLMF, anticorps CLMF2, anticorps IL-12B, anticorps NKSF, anticorps NKSF2, anticorps p40, anticorps Il-12b, anticorps Il12p40, anticorps Il-12p40, anticorps Il12, anticorps IL-12p40, anticorps IL-12, anticorps LOC100217488, anticorps IL-12p35, anticorps Il-12a, anticorps Ll12a, anticorps p35, anticorps IL12p40, anticorps IL12B, anticorps IL-12 p35, anticorps interleukin 12B, anticorps interleukin 12A, anticorps interleukin 12b, anticorps interleukin 12a, anticorps Interleukin 12 level, anticorps IL12B, anticorps IL12A, anticorps Il12b, anticorps Il12a, anticorps IL12, anticorps il12a
    Pathways
    Signalistation JAK/STAT, Signalisation TLR, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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