AIM2 anticorps (AA 255-354) (PE)

N° du produit ABIN2690017

Cet anticorps Lapin Polyclonal détecte spécifiquement AIM2 dans WB et FACS. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour AIM2 anticorps (AA 255-354) (PE) (ABIN2690017)

Antigène: AIM2 (Absent in Melanoma 2 (AIM2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AIM2 est conjugé à/à la PE

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-AIM2 anticorps (PE)

Épitope: AA 255-354

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse AIM2

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur AIM2

Antigène: AIM2 (Absent in Melanoma 2 (AIM2))

Autre désignation: AIM2

Sujet:

Synonyms: Gm1313, Ifi210, Interferon-inducible protein AIM2, Interferon-inducible protein 210, Ifi-210, Interferon-inducible protein p210, Aim2

Background: Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8.

ID gène: 383619

UniProt: Q91VJ1

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome