AIM2 anticorps (AA 255-354) (PE)
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- Antigène Voir toutes AIM2 Anticorps
- AIM2 (Absent in Melanoma 2 (AIM2))
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Épitope
- AA 255-354
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp AIM2 est conjugé à/à la PE
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from mouse AIM2
- Isotype
- IgG
- Top Product
- Discover our top product AIM2 Anticorps primaire
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- Indications d'application
- FCM 1:20-100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- AIM2 (Absent in Melanoma 2 (AIM2))
- Autre désignation
- AIM2 (AIM2 Produits)
- Synonymes
- anticorps AIM2, anticorps PYHIN4, anticorps Gm1313, anticorps Ifi210, anticorps absent in melanoma 2, anticorps AIM2, anticorps Aim2
- Sujet
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Synonyms: Gm1313, Ifi210, Interferon-inducible protein AIM2, Interferon-inducible protein 210, Ifi-210, Interferon-inducible protein p210, Aim2
Background: Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8.
- ID gène
- 383619
- UniProt
- Q91VJ1
- Pathways
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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