COPG 1/ 2 (AA 80-130) anticorps

Détails pour le produit réf. ABIN2690048
Antigène
Épitope
AA 80-130
2
Reactivité
Humain, Souris, Rat (Rattus)
2
2
2
Hôte
Lapin
2
Clonalité
Polyclonal
Conjugué
Inconjugué
1
1
Application
Western Blotting (WB)
2
Options
Immunogène KLH conjugated synthetic peptide derived from human COPG1
Isotype IgG
Purification Purified by Protein A.
Antigène
Sujet

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte triglyceride lipase (PNPLA2) with the lipid droplet surface to mediate lipolysis (By similarity).

Subcellular location: Cytoplasm, Membrane bound

Synonyms: Gamma-2-COP, Gamma-2-coat protein, Coatomer subunit gamma-2, Gamma-1-COP, Gamma-1-coat protein, Coatomer subunit gamma-1.

ID gène 22820, 26958
Indications d'application WB 1:100-1000
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at -20°C
Date de péremption 12 months
Images (Fournisseur)
Image no. 1 for anti-COPG 1/ 2 (AA 80-130) antibody (ABIN2690048) Mouse intestine lysates probed with Rabbit Anti-COPG Polyclonal Antibody, Unconjugate...
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