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CD11b anticorps

GMP Grade ITGAM Reactivité: Humain FACS Hôte: Souris Monoclonal OKM1 unconjugated
N° du produit ABIN2704154
  • Antigène Voir toutes CD11b (ITGAM) Anticorps
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivité
    • 279
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    • 17
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    Humain
    Hôte
    • 154
    • 114
    • 105
    • 4
    • 1
    • 1
    Souris
    Clonalité
    • 279
    • 96
    • 1
    Monoclonal
    Conjugué
    • 125
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    • 2
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    • 1
    • 1
    • 1
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    • 1
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    Cet anticorp CD11b est non-conjugé
    Application
    • 279
    • 88
    • 79
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    Flow Cytometry (FACS)
    Attributs du produit
    The clone OKM1, a mouse monoclonal antibody, binds with a 165 kDa adhesion glycoprotein present in human cells known as CD11b. CD11b associates with the 95 kDa integrin β2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2), and CD50 (ICAM-3).
    Purification
    Purified
    Pureté
    >95 %
    Classe de qualité
    GMP Grade
    Immunogène
    Human PBMC
    Clone
    OKM1
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product ITGAM Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
  • Antigène
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Autre désignation
    CD11b (ITGAM Produits)
    Synonymes
    anticorps CD11b/CD18, anticorps CR3, anticorps CR3A, anticorps Cd11b, anticorps F730045J24Rik, anticorps Ly-40, anticorps MAC1, anticorps Mac-1, anticorps Mac-1a, anticorps CD11B, anticorps MAC-1, anticorps MAC1A, anticorps MO1A, anticorps SLEB6, anticorps C3bi, anticorps integrin subunit alpha M, anticorps integrin alpha M, anticorps integrin, alpha M (complement component 3 receptor 3 subunit), anticorps integrin alpha-M, anticorps ITGAM, anticorps Itgam, anticorps LOC100351865
    Sujet
    CD11b is a 165- kDa adhesion glycoprotein that associates with the 95- kDa integrin β2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3).The OKM1 directed against the CD11b antigen on human monocytes and granulocytes.
    NCBI Accession
    NM_000632
    UniProt
    P11215
    Pathways
    Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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