RFXANK anticorps

N° du produit ABIN2716147

Détail du produit anti-RFXANK anticorps

Antigène: RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RFXANK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Attributs du produit: Homo sapiens regulatory factor X-associated ankyrin-containing protein (RFXANK), transcript variant 2

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human RFXANK(NP_604389) produced in HEK293T cell

Clone: 2G7

Isotype: IgG2a

Information d'application

Indications d'application: WB 1:2000, IHC 1:150,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur RFXANK

Antigène: RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))

Autre désignation: RFXANK (RFXANK Produits)

Synonymes: anticorps ANKRA1, anticorps BLS, anticorps F14150_1, anticorps RFX-B, anticorps Tvl1, anticorps regulatory factor X associated ankyrin containing protein, anticorps regulatory factor X-associated ankyrin-containing protein, anticorps RFXANK, anticorps Rfxank

Sujet: Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity.

Poids moléculaire: 25.4 kDa

ID gène: 8625

NCBI Accession: NM_134440

HGNC: 8625