SAE1 anticorps

N° du produit ABIN271943

Détail du produit anti-SAE1 anticorps

Antigène: SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAE1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of AOS1 protein. (region surrounding Leu247)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IF: 1: 50-1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur SAE1

Antigène: SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))

Autre désignation: SAE1 / AOS1 (SAE1 Produits)

Synonymes: anticorps AOS1, anticorps HSPC140, anticorps SUA1, anticorps UBLE1A, anticorps 2400010M20Rik, anticorps 2610044L12Rik, anticorps AL033372, anticorps AW743391, anticorps D7Ertd177e, anticorps Sua1, anticorps Uble1a, anticorps Aos1p, anticorps Sua1p, anticorps aos, anticorps sae2a, anticorps uble1a, anticorps wu:fa28b04, anticorps zgc:86633, anticorps SUMO1 activating enzyme subunit 1, anticorps SUMO1 activating enzyme subunit 1 L homeolog, anticorps SAE1, anticorps Sae1, anticorps sae1.L, anticorps sae1

Sujet: Proteolytic degradation by the ubiquitin (Ub) system is essential for normal cell cycle progression, cellular differentiation and stress responses. Proteins conjugated to Ub are marked for progressive degradation by the 26S Proteosome. Ubiquitin-like 1-activating enzyme E1A, also designated SUMO-1-activating enzyme or AOS-1, belongs to the ubiquitin-activating E1 family of proteins and plays an important role in the first step of the UBL1 conjugation pathway. AOS-1, which is a dimeric enzyme, functions as a UBLI E1 ligase, mediating the ATP-dependent activation of UBL1. It can bind with UBLE1A and UBLE1B to form a heterodimer which can bind UBL1.Synonyms: SUA1, SUMO-activating enzyme subunit 1, UBLE1A, Ubiquitin-like 1-activating enzyme E1A

Poids moléculaire: approx. 38 kDa

ID gène: 10055

NCBI Accession: NP_005491

UniProt: Q9UBE0