DLGAP1 anticorps

N° du produit ABIN272131

Détail du produit anti-DLGAP1 anticorps

Antigène: DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLGAP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of SAPAP1 protein. (region surrounding Glu817)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 10000. Western blot: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur DLGAP1

Antigène: DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

Autre désignation: DLGAP1 / SAPAP1 (DLGAP1 Produits)

Synonymes: anticorps DKFZp469D0713, anticorps gkap, anticorps sapap1, anticorps DAP-1, anticorps DAP-1-ALPHA, anticorps DAP-1-BETA, anticorps GKAP, anticorps SAPAP1, anticorps hGKAP, anticorps 4933422O14Rik, anticorps 9630002F18, anticorps AI845682, anticorps AI848168, anticorps BB075781, anticorps D17Bwg0511e, anticorps GKAP/SAPAP, anticorps GKPA/SAPAP, anticorps Gkap, anticorps Sapap1, anticorps mKIAA4162, anticorps DLG associated protein 1, anticorps discs, large (Drosophila) homolog-associated protein 1, anticorps disks large-associated protein 1, anticorps discs, large homolog-associated protein 1, anticorps discs, large (Drosophila) homolog-associated protein 1b, anticorps DLGAP1, anticorps LOC100408093, anticorps LOC100548434, anticorps dlgap1, anticorps Dlgap1, anticorps dlgap1b

Sujet: Members of the postsynaptic density-95 (PSD-95)/SAP90 family of membraneassociated guanylate kinase (MAGUK) proteins function as multimodular scaffolds that organize protein-signaling complexes at neuronal synapses. PSD-95/SAP90 binds guanylate kinase-associated protein (GKAP), also designated GK domain-binding protein, DAP-1-α, DAP-1-β, PSD-95 binding protein, PSD-95/SAP90 associated protein, or SAPAP1, through the guanylate kinase domain. SAPAP1 is expressed widely in neurons of the cortex and hippocampus and in the Purkinje and granule cells of the cerebellum. N-terminal splice variants of SAPAP1 are expressed as 95 and 130 kDa proteins. SAPAP1 is localized specifically in the PSD of glutamatergic synapses, consistent with its direct interaction with PSD-95 family proteins.Synonyms: DAP-1, DAP1, Disks large-associated protein 1, GKAP, Guanylate kinase-associated protein, PSD-95/SAP90-binding protein 1, SAP90/PSD-95-associated protein 1

Poids moléculaire: approx. 108 kDa

ID gène: 9229

NCBI Accession: NP_001003809

UniProt: O14490