CDKL1 anticorps

N° du produit ABIN272207

Détail du produit anti-CDKL1 anticorps

Antigène: CDKL1 (Cyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase) (CDKL1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDKL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of KKIALRE protein. (region surrounding asn301)

Réactivité croisée (Details): Species reactivity (tested):Human, Rat.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CDKL1

Antigène: CDKL1 (Cyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase) (CDKL1))

Autre désignation: CDKL1 (CDKL1 Produits)

Synonymes: anticorps CDKL1, anticorps KKIALRE, anticorps P42, anticorps 4933411O17Rik, anticorps cyclin dependent kinase like 1, anticorps cyclin-dependent kinase-like 1 (CDC2-related kinase), anticorps CDKL1, anticorps cdkl1, anticorps Cdkl1

Sujet: The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated by the MAP kinases ERK 1 and ERK 2. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group of proteins and is closely related to p42 KKIALRE. KKIAMRE is predominantly expressed in testis, kidney, brain and lung. KKIAMRE contains the conserved MAP kinase dual phosphorylation motif in the sequence Thr-Asp-Tyr and is activated by treatment of cells by EGF. However, unlike other MAP kinases, the EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.Synonyms: Cyclin-dependent kinase-like 1, KKIALRE, Protein kinase p42 KKIALRE, Serine/threonine-protein kinase KKIALRE

Poids moléculaire: approx. 42 kDa

ID gène: 8814

NCBI Accession: NP_004187

UniProt: Q00532