HDAC6 anticorps

N° du produit ABIN2722516

Détail du produit anti-HDAC6 anticorps

Antigène: HDAC6 (Histone Deacetylase 6 (HDAC6))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HDAC6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Attributs du produit: Homo sapiens histone deacetylase 6 (HDAC6)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human HDAC6 (NP_006035) produced in HEK293T cell.

Clone: 3E7

Isotype: IgG1

Information d'application

Indications d'application: WB 1:500~1000, IHC 1:150, FLOW 1:100

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-HDAC6 (ABIN2722516)

Wang, Hu, Tang, Xie: "HDAC6-mediated EGFR stabilization and activation restrict cell response to sorafenib in non-small cell lung cancer cells." dans: Medical oncology (Northwood, London, England), Vol. 33, Issue 5, pp. 50, (2016) (PubMed).

Détails sur HDAC6

Antigène: HDAC6 (Histone Deacetylase 6 (HDAC6))

Autre désignation: HDAC6 (HDAC6 Produits)

Synonymes: anticorps HD6, anticorps Hd6, anticorps Hdac5, anticorps Sfc6, anticorps mHDA2, anticorps CG6170, anticorps DHDAC2, anticorps DmHDAC2, anticorps Dmel\\CG6170, anticorps HDAC, anticorps HDAC2, anticorps dHDAC2, anticorps dHDAC6, anticorps dmHDA404, anticorps hdac6, anticorps MGC53140, anticorps wu:fc31d02, anticorps dsim_GLEANR_17355, anticorps DsimGD17207, anticorps GD17207, anticorps HDAC6, anticorps ATHDA6, anticorps AXE1, anticorps HISTONE DEACETYLASE 6, anticorps MDC12.7, anticorps MDC12_7, anticorps RNA-MEDIATED TRANSCRIPTIONAL SILENCING 1, anticorps RPD3B, anticorps RTS1, anticorps SIL1, anticorps histone deacetylase 6, anticorps histone deacetylase 6, anticorps Histone deacetylase 6, anticorps histone deacetylase 6 L homeolog, anticorps GD17207 gene product from transcript GD17207-RB, anticorps Histone DeAcetylase, anticorps HDAC6, anticorps Hdac6, anticorps hdac6.L, anticorps hdac6, anticorps Dsim\HDAC6, anticorps PTRG_03035, anticorps HDA6, anticorps hda-6

Sujet: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Poids moléculaire: 131.2 kDa

ID gène: 10013

NCBI Accession: NM_006044

HGNC: 10013

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling