Serotonin Receptor 1A anticorps

N° du produit ABIN272268

Détail du produit anti-Serotonin Receptor 1A anticorps

Antigène: Serotonin Receptor 1A (HTR1A)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 1A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of SR-1A protein. (region surrounding Phe321)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 90 % pure SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Serotonin Receptor 1A

Antigène: Serotonin Receptor 1A (HTR1A)

Abstract: HTR1A Produits

Synonymes: anticorps 5-HT-dro2A, anticorps 5-HT1ADro, anticorps 5-HT[1A]Dro, anticorps 5-HT[[1ADro]], anticorps 5-HT[[1A]], anticorps 5-HT[[1A]]DRO, anticorps 5HT-R2A, anticorps 5HT-dro2A, anticorps 5HT-drp[[2A]], anticorps 5HT1A, anticorps 5HT[[1ADro]], anticorps 5htdro2a, anticorps CG16720, anticorps DRO2A, anticorps Dm5HTdro2A, anticorps Dmel\\CG16720, anticorps d5-HT1A, anticorps 5htr1a, anticorps htr1a, anticorps HTR1A, anticorps Htr1a, anticorps 5-Ht1a, anticorps Gpcr18, anticorps 5-HT-1A, anticorps 5-HT1A, anticorps 5HT1a, anticorps ADRB2RL1, anticorps ADRBRL1, anticorps G-21, anticorps PFMCD, anticorps RAT5HT1A, anticorps 5ht1a, anticorps adrb2rl1, anticorps adrbrl1, anticorps htr1a-A, anticorps 5-hydroxytryptamine (serotonin) receptor 1A, anticorps 5-hydroxytryptamine receptor 1A, anticorps 5-hydroxytryptamine (serotonin) receptor 1A a, anticorps 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled L homeolog, anticorps 5-HT1A, anticorps HTR1A, anticorps htr1aa, anticorps Htr1a, anticorps htr1a.L

Sujet: The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. β-adrenergic bound to adrenaline activates adenylyl cyclase, while α2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the α2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories,designated SR-1-7 (5HT1-7). Subtypes within the SR-1 group include SR-1A,-1B, -1D, -1E and -1F.Synonyms: 5-HT-1A, 5-HT1A, 5-hydroxytryptamine receptor 1A, ADRB2RL1, ADRBRL1

Poids moléculaire: approx. 46 kDa

ID gène: 3350

NCBI Accession: NP_000515

UniProt: P08908

Pathways: Signalistation JAK/STAT, Synaptic Membrane, Feeding Behaviour