PTPN7 anticorps

N° du produit ABIN2730123

Détail du produit anti-PTPN7 anticorps

Antigène: PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PTPN7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: Homo sapiens protein tyrosine phosphatase, non-receptor type 7 (PTPN7), transcript variant 2

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human PTPN7(NP_542155) produced in HEK293T cell.

Clone: 3B10

Isotype: IgG2b

Information d'application

Indications d'application: WB 1:500~2000, IF 1:100,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur PTPN7

Antigène: PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))

Autre désignation: PTPN7 (PTPN7 Produits)

Synonymes: anticorps BPTP-4, anticorps HEPTP, anticorps LC-PTP, anticorps LPTP, anticorps PTPNI, anticorps C920001D21Rik, anticorps Heptp, anticorps Lcptp, anticorps protein tyrosine phosphatase, non-receptor type 7, anticorps PTPN7, anticorps Ptpn7

Sujet: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene.

Poids moléculaire: 44.8 kDa

ID gène: 5778

NCBI Accession: NM_080588

HGNC: 5778