CD3 epsilon anticorps

N° du produit ABIN2739341

Cet anticorps Lapin Polyclonal détecte spécifiquement CD3 epsilon dans FACS, WB et IP. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Porc, Singe, Boeuf (Vache), Cheval, Lapin, Mouton, Hamster et Orang-Utan.

Aperçu rapide pour CD3 epsilon anticorps (ABIN2739341)

Antigène: CD3 epsilon (CD3E)

Reactivité: Humain, Souris, Rat, Porc, Singe, Boeuf (Vache), Cheval, Lapin, Mouton, Hamster, Orang-Utan

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD3 epsilon est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-CD3 epsilon anticorps

Specificité: Mouse CD3e.

Purification: Protein A purified

Immunogène: Amino acids ERPPPVPNPDYEP (156-168). Percent identity by BLAST analysis: Human, Orangutan, Monkey, Galago, Marmoset, Mouse, Rat, Sheep, Hamster, Elephant, Rabbit, Pig (100%), Chimpanzee, Gorilla, Ferret, Cat, Chicken, Dog (92%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Information d'application

Indications d'application: Approved: Flo (0.5 - 1 μg/10 x10⁶), IP, WB (0.5 - 1 μg/mL)

Usage: This antibody recognizes the epsilon-chain of CD3 (CD3e), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28  kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the Tcell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the Tcell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the Tcell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the Tcell surface. CD3 antigen is a highly specific marker for Tcells, and is present in majority of Tcell neoplasms.

Commentaires:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2°C to 8°C.

Détails sur CD3 epsilon

Antigène: CD3 epsilon (CD3E)

Autre désignation: CD3E

Sujet: Name/Gene ID: CD3E

Synonyms: CD3E, CD3e antigen, CD3-epsilon, T-cell receptor epsilon chain, TCRE, T-cell receptors epsilon chain, T3E, CD3 Epsilon

ID gène: 916

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway