CD11b anticorps

N° du produit ABIN2742255

Cet anticorps anti-CD11b est un anticorps Rat Monoclonal détectant CD11b dans FACS, IHC, IP, IF, IHC (fro), ELISA, Func et BR. Adapté pour Humain, Souris, Lapin, Babouin, Macaque rhésus, Chimpanzé et Cynomolgus.

Aperçu rapide pour CD11b anticorps (ABIN2742255)

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivité: Humain, Souris, Lapin, Babouin, Macaque rhésus, Chimpanzé, Cynomolgus

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD11b est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), ELISA, Functional Studies (Func), Blocking Reagent (BR)

Clone: M1-70

Détail du produit anti-CD11b anticorps

Specificité: Mouse ITGAM / CD11b

Purification: Protein G purified

Immunogène: B10 mouse spleen cells enriched for T lymphocytes.

Type of Immunogen: Cells

Isotype: IgG2b kappa

Information d'application

Indications d'application: Approved: Block, ELISA, Flo (0.5 - 1 μg/10 x10⁶), Func, IF (0.5 - 1 μg/mL), IHC, IHC-Fr (0.5 - 1 μg/mL), IP

Usage: CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin alpha-M (CD11b) combines with the Integrin beta-2 (CD18) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin alpha-M/beta-2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. ELISA: Order BSA-free antibody format for coating.

Commentaires:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2°C to 8°C.

Détails sur CD11b

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Autre désignation: ITGAM / CD11b

Sujet: Name/Gene ID: ITGAM
Family: Integrin

Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

ID gène: 3684

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation