CD11b anticorps
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- Antigène Voir toutes CD11b (ITGAM) Anticorps
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Reactivité
- Humain, Souris, Lapin, Babouin, Macaque rhésus, Chimpanzé, Cynomolgus
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD11b est non-conjugé
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Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), ELISA, Functional Studies (Func), Blocking Reagent (BR)
- Specificité
- Mouse ITGAM / CD11b
- Purification
- Protein G purified
- Immunogène
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B10 mouse spleen cells enriched for T lymphocytes.
Type of Immunogen: Cells - Clone
- M1-70
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product ITGAM Anticorps primaire
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- Indications d'application
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Approved: Block, ELISA, Flo (0.5 - 1 μg/10 x106), Func, IF (0.5 - 1 μg/mL), IHC, IHC-Fr (0.5 - 1 μg/mL), IP
Usage: CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin alpha-M (CD11b) combines with the Integrin beta-2 (CD18) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin alpha-M/beta-2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. ELISA: Order BSA-free antibody format for coating. - Commentaires
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Target Species of Antibody: Mouse
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2°C to 8°C.
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- Antigène
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Autre désignation
- ITGAM / CD11b (ITGAM Produits)
- Synonymes
- anticorps CD11b/CD18, anticorps CR3, anticorps CR3A, anticorps Cd11b, anticorps F730045J24Rik, anticorps Ly-40, anticorps MAC1, anticorps Mac-1, anticorps Mac-1a, anticorps CD11B, anticorps MAC-1, anticorps MAC1A, anticorps MO1A, anticorps SLEB6, anticorps C3bi, anticorps integrin subunit alpha M, anticorps integrin alpha M, anticorps integrin, alpha M (complement component 3 receptor 3 subunit), anticorps integrin alpha-M, anticorps ITGAM, anticorps Itgam, anticorps LOC100351865
- Sujet
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Name/Gene ID: ITGAM
Family: Integrin
Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain - ID gène
- 3684
- Pathways
- Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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