Migration-inducing gene 15 protein, MLD, dihydroceramide desaturase, sphingolipid delta 4 desaturase, DES1, MGC5079, DEGS,The product of the DEGS1 gene is a member of the membrane fatty acid (sphingolipid delta 4) desaturase family. Reported to function by inserting double bonds at delta 4 position in fatty acids. DEGS1 is an intracellular enzyme. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified.
Purification
Antigen Immunoaffiinity Purification
Immunogène
Synthetic peptide derived from the human DEGS1 protein
Isotype
IgG
Indications d'application
Antibody can be used for Western blotting (1:400 starting dilution) and immunohistochemistry (10-15 μg/mL). Optimal concentration should be evaluated by serial dilutions.
Restrictions
For Research Use only
Concentration
Lot specific
Buffer
Provided as solution in Tris buffered saline with 0.08 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles