PPAP2B anticorps

N° du produit ABIN2764066

Détail du produit anti-PPAP2B anticorps

Antigène: PPAP2B (Phosphatidic Acid Phosphatase Type 2B (PPAP2B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPAP2B est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: PAP2B,Vascular endothelial growth factor and type I collagen inducible protein (VCIP), also known as phosphatidic acid phosphatase 2b (PAP2b), was originally identified in a functional assay of angiogenesis. VCIP/PAP2b exhibits an ArgGlyAsp (RGD) cell adhesion sequence. Immunoprecipitation and fluorescence-activated cell sorting analyses demonstrated that VCIP-RGD is exposed to the outside of the cell surface. Retroviral transduction of VCIP can induce cell aggregation and cell cell interactions, modestly increase p120 catenin expression and promote activation of the Fak, Akt and GSK3 protein kinases. Expression of VCIP promoted adhesion, spreading and tyrosine phosphorylation of Fak, Shc, Cas and paxillin in endothelial cells. PAP2b/VCIP is expressed in close proximity to vascular endothelial growth factor, von Willebrand factor and {alpha}v3 integrin in tumor vasculatures.

Purification: Antigen Immunoaffiinity Purification

Immunogène: Synthetic peptide derived from the phosphatidic acid phosphatase 2B protein

Isotype: IgG

Information d'application

Indications d'application: Antibody can be used for Western blotting (see vial for dilution) and EIA. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur PPAP2B

Antigène: PPAP2B (Phosphatidic Acid Phosphatase Type 2B (PPAP2B))

Autre désignation: Phosphatidic Acid Phosphatase 2B (PPAP2B Produits)

Synonymes: anticorps Dri42, anticorps LPP3, anticorps PAP2B, anticorps VCIP, anticorps 1110003O22Rik, anticorps 2610002D05Rik, anticorps AV025606, anticorps D4Bwg0538e, anticorps D4Bwg1535e, anticorps Lpp3, anticorps Ppab2b, anticorps dri42, anticorps lpp3, anticorps pap2b, anticorps ppap2bb, anticorps vcip, anticorps ppap2b, anticorps ppap2ba, anticorps PPAP2B, anticorps si:dkey-19f4.1, anticorps phospholipid phosphatase 3, anticorps phospholipid phosphatase 3 L homeolog, anticorps phospholipid phosphatase 3 S homeolog, anticorps PLPP3, anticorps Plpp3, anticorps plpp3.L, anticorps plpp3.S, anticorps plpp3

UniProt: O14495