CSK anticorps (Middle Region)

N° du produit ABIN2774001

Cet anticorps Lapin Polyclonal détecte spécifiquement CSK dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien, Cobaye et Cheval.

Aperçu rapide pour CSK anticorps (Middle Region) (ABIN2774001)

Antigène: CSK (C-Src tyrosine Kinase (CSK))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CSK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-CSK anticorps

Épitope: Middle Region

Séquence: SEDNVAKVSD FGLTKEASST QDTGKLPVKW TAPEALREKK FSTKSDVWSF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CSK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CSK

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 450 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CSK

Antigène: CSK (C-Src tyrosine Kinase (CSK))

Autre désignation: CSK

Sujet: CSK specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site.CSK can also act on the LYN and FYN kinases.
Alias Symbols: MGC117393
Protein Interaction Partner: UBC, EGFR, TNRC6B, PAG1, RGS16, ZAP70, CD247, CD3E, KHDRBS1, TENC1, FRK, ARRB2, ARRB1, AKT1, GRB2, VCP, ID3, FHL2, SRCIN1, ZNF212, G3BP1, UBASH3B, SHC1, CBL, JUN, ELAVL1, Csk, MAPK15, DOK3, PTPN22, PTPN18, SIT1, TLR3, LAIR1, DOK1, PXN, PLD2, PRKACA, DAB2,
Protein Size: 450

Poids moléculaire: 51 kDa

ID gène: 1445

NCBI Accession: NM_004383, NP_004374

UniProt: P41240

Pathways: TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events