UACA anticorps (C-Term)

N° du produit ABIN2774333

Détail du produit anti-UACA anticorps

Antigène: UACA

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UACA est non-conjugé

Application: Western Blotting (WB)

Séquence: TELLNDVERL KQALNGLSQL TYTSGNPTKR QSQLIDTLQH QVKSLEQQLA

Homologie: Cow: 100%, Dog: 85%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 85%, Rabbit: 92%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against UACA. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1403 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur UACA

Antigène: UACA

Autre désignation: UACA (UACA Produits)

Synonymes: anticorps NUCLING, anticorps 2700059D02Rik, anticorps nucling, anticorps RGD1560011, anticorps uveal autoantigen with coiled-coil domains and ankyrin repeats, anticorps UACA, anticorps Uaca

Sujet: UACA regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. It promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. It regulates the redistribution of APAF1 into the nucleus after proapoptotic stress and down-regulates the expression of LGALS3 by inhibiting NFKB1.
Alias Symbols: FLJ10128, KIAA1561, MGC141967, MGC141969, NUCLING
Protein Interaction Partner: KRT40, FUS, RNF2, HIF1AN, PAN2, TP63, UBC, USP48, RABEP1, STAMBP, FBXO25, NRD1, Mprip, MED14, CELSR3,
Protein Size: 1403

Poids moléculaire: 154 kDa

ID gène: 55075

NCBI Accession: NM_001008224, NP_001008225

UniProt: Q9BZF9

Pathways: Positive Regulation of Endopeptidase Activity