FGF8 anticorps (C-Term)

N° du produit ABIN2774365

Détail du produit anti-FGF8 anticorps

Antigène: FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Lapin, Cobaye, Porc, Poisson zèbre (Danio rerio), Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGF8 est non-conjugé

Application: Western Blotting (WB)

Séquence: EGWYMAFTRK GRPRKGSKTR QHQREVHFMK RLPRGHHTTE QSLRFEFLNY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 75%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 75%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against FGF8. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 215 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FGF8

Antigène: FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))

Autre désignation: FGF8 (FGF8 Produits)

Synonymes: anticorps Aigf, anticorps Fgf-8, anticorps AIGF, anticorps FGF-8, anticorps HBGF-8, anticorps HH6, anticorps KAL6, anticorps fibroblast growth factor 8, anticorps Fgf8, anticorps FGF8

Sujet: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.
Alias Symbols: AIGF, HBGF-8, KAL6, MGC149376, FGF-8
Protein Interaction Partner: FGFR2, FGFR1, FGFR4, FGFR3, AR,
Protein Size: 215

Poids moléculaire: 22 kDa

ID gène: 2253

NCBI Accession: NM_006119, NP_006110

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis