PDGFA anticorps (C-Term)

N° du produit ABIN2774382

Cet anticorps anti-PDGFA Polyclonal Lapin (ABIN2774382) détecte spécifiquement PDGFA dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien et Cobaye.

Aperçu rapide pour PDGFA anticorps (C-Term) (ABIN2774382)

Antigène: PDGFA (Platelet Derived Growth Factor A (PDGFA))

Reactivité: Humain, Souris, Rat, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDGFA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PDGFA anticorps

Épitope: C-Term

Séquence: HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTDVR

Homologie: Dog: 85%, Guinea Pig: 82%, Human: 100%, Mouse: 85%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against PDGFA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PDGFA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PDGFA

Antigène: PDGFA (Platelet Derived Growth Factor A (PDGFA))

Autre désignation: PDGFA

Sujet: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis, knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene.
Alias Symbols: PDGF-A, PDGF1
Protein Interaction Partner: COL6A1, COL5A1, COL4A1, COL3A1, COL2A1, COL1A2, COL1A1, PDAP1, DUSP3, SPARC, PDGFRA, PDGFA, HSPG2, FURIN, A2M, PLCG1,
Protein Size: 196

Poids moléculaire: 21 kDa

ID gène: 5154

NCBI Accession: NM_033023, NP_148983

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling