EIF2AK2 anticorps (Middle Region)

N° du produit ABIN2774645

Cet anticorps anti-EIF2AK2 Polyclonal Lapin (ABIN2774645) détecte spécifiquement EIF2AK2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval et Porc.

Aperçu rapide pour EIF2AK2 anticorps (Middle Region) (ABIN2774645)

Antigène: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF2AK2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-EIF2AK2 anticorps

Épitope: Middle Region

Séquence: QVFKAKHRID GKTYVIKRVK YNNEKAEREV KALAKLDHVN IVHYNGCWDG

Homologie: Cow: 92%, Dog: 83%, Horse: 91%, Human: 100%, Mouse: 83%, Pig: 83%, Rabbit: 100%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against EIF2AK2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human EIF2AK2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 551 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur EIF2AK2

Antigène: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Autre désignation: EIF2AK2

Sujet: EIF2AK2 might play a role in ER stress-induced apoptosis and in Alzheimer's disease. Alzheimer cases show prominent EIF2AK2 activation in association with neuritic plaques and pyramidal neurons in the hippocampus and neocortex.
Alias Symbols: EIF2AK1, MGC126524, PKR, PRKR
Protein Interaction Partner: UBC, TRAF6, TRAF5, TRAF2, EGFR, DHX9, STAU2, PRKRA, EIF2AK2, HECW2, TOP1, STAU1, DICER1, DHX30, EBNA1BP2, IGF2BP2, IGF2BP3, PABPC4, MOV10, ILF3, ILF2, HSP90AA1, EIF2A, NOC3L, GNL3, NOP2, HNRNPC, HIST1H1C, ELAVL1, NPM1, IL7R, gag, Jak2, TYK2, JAK1, EIF2S1,
Protein Size: 551

Poids moléculaire: 62 kDa

ID gène: 5610

NCBI Accession: NM_002759, NP_002750

UniProt: P19525

Pathways: Réparation de l'ADN, ER-Nucleus Signaling, Hepatitis C