CD8B anticorps (Middle Region)

N° du produit ABIN2775291

Cet anticorps anti-CD8B Polyclonal Lapin (ABIN2775291) détecte spécifiquement CD8B dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Chien et Lapin.

Aperçu rapide pour CD8B anticorps (Middle Region) (ABIN2775291)

Antigène: CD8B (CD8b Molecule (CD8B))

Reactivité: Humain, Rat, Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD8B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD8B anticorps

Épitope: Middle Region

Fonction: CD8B Antibody - middle region

Séquence: KPEDSGIYFC MIVGSPELTF GKGTQLSVVD FLPTTAQPTK KSTLKKRVCR

Homologie: Dog: 79%, Human: 100%, Rabbit: 93%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against CD8B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CD8B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42205-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD8B

Antigène: CD8B (CD8b Molecule (CD8B))

Autre désignation: CD8B

Sujet:

Background Information: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8B is the CD8 beta chain isoforms.

Gene Name: CD8b molecule

Alternative Symbols: LY3, P37, LEU2, LYT3, CD8B1

Protein Name: T-cell surface glycoprotein CD8 beta chain

Poids moléculaire: 21kDa

ID gène: 926

NCBI Accession: NP_004922

UniProt: P10966

Pathways: TCR Signaling