NAMPT anticorps (C-Term)

N° du produit ABIN2775322

Cité dans 1 publication. Cet anticorps anti-NAMPT Polyclonal Lapin (ABIN2775322) détecte spécifiquement NAMPT dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Poisson zèbre (Danio rerio), Chien, Cobaye, Boeuf (Vache), Cheval et Lapin.

Aperçu rapide pour NAMPT anticorps (C-Term) (ABIN2775322)

Antigène: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Reactivité: Humain, Rat, Souris, Poisson zèbre (Danio rerio), Chien, Cobaye, Boeuf (Vache), Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAMPT est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-NAMPT anticorps

Épitope: C-Term

Fonction: PBEF1 Antibody - C-terminal region

Séquence: VTLEEGKGDL EEYGQDLLHT VFKNGKVTKS YSFDEIRKNA QLNIELEAAH

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against PBEF1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human PBEF1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8106485

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-NAMPT (ABIN2775322)

Xia, Weisenburger, Koch, Burkart, Reifenberg, Förstermann, Li: "Restoration of perivascular adipose tissue function in diet-induced obese mice without changing bodyweight." dans: British journal of pharmacology, Vol. 174, Issue 20, pp. 3443-3453, (2017) (PubMed).

Détails sur NAMPT

Antigène: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Autre désignation: PBEF1

Sujet:

Background Information: PBEF1 catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

Gene Name: Nicotinamide phosphoribosyltransferase

Alternative Symbols: VF, PBEF, PBEF1, VISFATIN, 1110035O14Rik

Protein Name: Nicotinamide phosphoribosyltransferase

Poids moléculaire: 54kDa

ID gène: 10135

NCBI Accession: NP_005737

UniProt: P43490