SMARCAL1 anticorps (Middle Region)

N° du produit ABIN2775720

Détail du produit anti-SMARCAL1 anticorps

Antigène: SMARCAL1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A-Like 1 (SMARCAL1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMARCAL1 est non-conjugé

Application: Western Blotting (WB)

Séquence: DLLESGREKF LVFAHHKVVL DAITQELERK HVQHIRIDGS TSSAEREDLC

Homologie: Cow: 92%, Dog: 85%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against SMARCAL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SMARCAL1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 954 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SMARCAL1

Antigène: SMARCAL1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A-Like 1 (SMARCAL1))

Autre désignation: SMARCAL1 (SMARCAL1 Produits)

Synonymes: anticorps SMARCAL1, anticorps im:7145331, anticorps si:ch211-239d11.1, anticorps harp, anticorps hharp, anticorps 6030401P21Rik, anticorps AI851716, anticorps Mharp, anticorps HARP, anticorps HHARP, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1, anticorps SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1, anticorps Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 L homeolog, anticorps SMARCAL1, anticorps smarcal1, anticorps Smarcal1, anticorps smarcal1.L

Sujet: SMARCAL1 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. Mutations in SMARCAL1 gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency. The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.
Alias Symbols: HARP, HHARP
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, SULT1A1, Cebpb,
Protein Size: 954

Poids moléculaire: 106 kDa

ID gène: 50485

NCBI Accession: NM_014140, NP_054859

UniProt: Q9NZC9

Pathways: Embryonic Body Morphogenesis