CACNA2D1 anticorps (Middle Region)

N° du produit ABIN2776091

Détail du produit anti-CACNA2D1 anticorps

Antigène: CACNA2D1 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CACNA2D1 est non-conjugé

Application: Western Blotting (WB)

Séquence: PKSQEPVTLD FLDAELENDI KVEIRNKMID GESGEKTFRT LVKSQDERYI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CACNA2D1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CACNA2D1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1091 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CACNA2D1 (ABIN2776091)

Tétreault, Bourdin, Briot, Segura, Lesage, Fiset, Parent: "Identification of Glycosylation Sites Essential for Surface Expression of the CaVα2δ1 Subunit and Modulation of the Cardiac CaV1.2 Channel Activity." dans: The Journal of biological chemistry, Vol. 291, Issue 9, pp. 4826-43, (2016) (PubMed).

Stotz, Barr, McRory, Chen, Jarvis, Zamponi: "Several structural domains contribute to the regulation of N-type calcium channel inactivation by the beta 3 subunit." dans: The Journal of biological chemistry, Vol. 279, Issue 5, pp. 3793-800, (2004) (PubMed).

Détails sur CACNA2D1

Antigène: CACNA2D1 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1))

Autre désignation: CACNA2D1 (CACNA2D1 Produits)

Synonymes: anticorps CACNA2D1, anticorps DKFZp469K2211, anticorps CACNA2, anticorps CACNL2A, anticorps CCHL2A, anticorps Ca(v)alpha2delta1, anticorps Cacna2, anticorps Cchl2a, anticorps CCHLA2, anticorps DHSCCA, anticorps calcium voltage-gated channel auxiliary subunit alpha2delta 1, anticorps calcium channel, voltage-dependent, alpha 2/delta subunit 1, anticorps calcium channel, voltage-dependent, alpha2/delta subunit 1, anticorps CACNA2D1, anticorps cacna2d1, anticorps Cacna2d1

Sujet: CACNA2D1 encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio.
Alias Symbols: CACNA2, CCHL2A, CACNL2A
Protein Interaction Partner: STT3B, RAB11A, NDUFS4, Cep76,
Protein Size: 1091

Poids moléculaire: 120 kDa

ID gène: 781

NCBI Accession: NM_000722, NP_000713

UniProt: P54289