KCNJ4 anticorps (Middle Region)

N° du produit ABIN2776173

Détail du produit anti-KCNJ4 anticorps

Antigène: KCNJ4 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 4 (KCNJ4))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNJ4 est non-conjugé

Application: Western Blotting (WB)

Séquence: AVAAGLGLEA GSKEEAGIIR MLEFGSHLDL ERMQASLPLD NISYRRESAI

Homologie: Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against KCNJ4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human KCNJ4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 445 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KCNJ4

Antigène: KCNJ4 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 4 (KCNJ4))

Autre désignation: KCNJ4 (KCNJ4 Produits)

Synonymes: anticorps KCNJ4, anticorps CKIR2.3, anticorps HIR, anticorps HIRK2, anticorps HRK1, anticorps IRK-3, anticorps IRK3, anticorps Kir2.3, anticorps Kcnf2, anticorps MB-IRK3, anticorps Hirk2, anticorps potassium voltage-gated channel subfamily J member 4, anticorps potassium inwardly-rectifying channel, subfamily J, member 4, anticorps KCNJ4, anticorps Kcnj4

Sujet: KCNJ4 is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have??een found for this gene. Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neuronsSeveral different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: HIR, HIRK2, HRK1, IRK3, Kir2.3, MGC142066, MGC142068, IRK-3
Protein Interaction Partner: SNTA1, LIN7B, GNGT2, DLG2, IL16, DLG4, DLG1, KCNJ2, CASK, PRKCD, LIN7C, LIN7A, DMD,
Protein Size: 445

Poids moléculaire: 49 kDa

ID gène: 3761

NCBI Accession: NM_004981, NP_004972

UniProt: P48050