TRPA1 anticorps (Middle Region)

N° du produit ABIN2776190

Détail du produit anti-TRPA1 anticorps

Antigène: TRPA1 (Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cobaye, Chien, Cheval, Boeuf (Vache), Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: KCTDRLDEDG NTALHFAARE GHAKAVALLL SHNADIVLNK QQASFLHLAL

Homologie: Cow: 93%, Dog: 90%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TRPA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TRPA1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1119 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TRPA1 (ABIN2776190)

Trevisan, Benemei, Materazzi, De Logu, De Siena, Fusi, Fortes Rossato, Coppi, Marone, Ferreira, Geppetti, Nassini: "TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes/macrophages and oxidative stress." dans: Brain : a journal of neurology, Vol. 139, Issue Pt 5, pp. 1361-77, (2016) (PubMed).

Kun, Perkecz, Knie, Sétáló, Tornóczki, Pintér, Bán: "TRPA1 receptor is upregulated in human oral lichen planus." dans: Oral diseases, Vol. 23, Issue 2, pp. 189-198, (2016) (PubMed).

Pierce, Ryals, Wang, Christianson: "Vaginal hypersensitivity and hypothalamic-pituitary-adrenal axis dysfunction as a result of neonatal maternal separation in female mice." dans: Neuroscience, Vol. 263, pp. 216-30, (2014) (PubMed).

Nassini, Pedretti, Moretto, Fusi, Carnini, Facchinetti, Viscomi, Pisano, Stokesberry, Brunmark, Svitacheva, McGarvey, Patacchini, Damholt, Geppetti, Materazzi: "Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation." dans: PLoS ONE, Vol. 7, Issue 8, pp. e42454, (2012) (PubMed).

Détails sur TRPA1

Antigène: TRPA1 (Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1))

Autre désignation: TRPA1 (TRPA1 Produits)

Synonymes: anticorps trpa1, anticorps ANKTM1, anticorps Anktm1, anticorps CG5751, anticorps CG5761, anticorps CT18073, anticorps DmTRPA1, anticorps Dmel\\CG5751, anticorps TRPA, anticorps TRPA1, anticorps TrpA, anticorps dANKTM1, anticorps dTRPA, anticorps dTRPA1, anticorps dTrpA, anticorps dTrpA1, anticorps dtrpA1, anticorps trpA1, anticorps GLEAN_02449, anticorps FEPS, anticorps transient receptor potential cation channel, subfamily A, member 1a, anticorps Transient receptor potential cation channel A1, anticorps transient receptor potential cation channel subfamily A member 1, anticorps transient receptor potential A1, anticorps tryptophan synthase subunit alpha 1, anticorps transient receptor potential cation channel, subfamily A, member 1, anticorps TRPA cation channel homolog, anticorps trpa1a, anticorps TrpA1, anticorps TRPA1, anticorps LOC658860, anticorps LOC694623, anticorps trpA1, anticorps trpa1, anticorps Trpa1, anticorps trpa-1

Sujet: The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined, however, studies indicate the function may involve a role in sig
Alias Symbols: ANKTM1
Protein Interaction Partner: UBC, CYLD,
Protein Size: 1119

Poids moléculaire: 127 kDa

ID gène: 8989

NCBI Accession: NM_007332, NP_015628

UniProt: O75762