KLF4 anticorps (N-Term)
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- Antigène Voir toutes KLF4 Anticorps
- KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))
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Épitope
- N-Term
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Reactivité
- Humain, Boeuf (Vache), Cheval, Chien, Mouton, Porc, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KLF4 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GAACGGSNLA PLPRRETEEF NDLLDLDFIL SNSLTHPPES VAATVSSSAS
- Homologie
- Cow: 80%, Dog: 87%, Horse: 87%, Human: 100%, Pig: 80%, Rabbit: 85%, Sheep: 80%
- Attributs du produit
- This is a rabbit polyclonal antibody against KLF4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human KLF4
- Top Product
- Discover our top product KLF4 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 470 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))
- Autre désignation
- KLF4 (KLF4 Produits)
- Synonymes
- anticorps EZF, anticorps GKLF, anticorps Gklf, anticorps Zie, anticorps KLF4, anticorps biklf, anticorps biklf-A, anticorps Kruppel like factor 4, anticorps Kruppel-like factor 4 (gut), anticorps Kruppel-like factor 4, anticorps Kruppel-like factor 4 (gut) L homeolog, anticorps KLF4, anticorps Klf4, anticorps klf4, anticorps klf4.L
- Sujet
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The mammalian Kruppel-like transcription factor, KLF4 is involved in preventing centrosome amplification following DNA damage caused by gamma-irradiation. It is both necessary and sufficient in preventing centrosome amplification following gamma-radiation-induced DNA damage and does so by transcriptionally suppressing cyclin E expression n. Kruppel-like factor 4 is also known to exhibit checkpoint function during the G1/S and G2/M transitions of the cell cycle.
Alias Symbols: EZF, GKLF
Protein Interaction Partner: EP300, CREBBP, SETD7, CTBP1, Dlg4, APP, CUL2, VHL, UBC, TCEB2, SP1, RELA, PRKCD, PPARG, SMARCA4, HDAC2, HDAC7, KAT5, HDAC1, HDAC5, ELK1, KLF6, TP53,
Protein Size: 470 - Poids moléculaire
- 50 kDa
- ID gène
- 9314
- NCBI Accession
- NM_004235, NP_004226
- UniProt
- O43474
- Pathways
- Peptide Hormone Metabolism, Stem Cell Maintenance
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