Insulin Receptor anticorps (Middle Region)
Aperçu rapide pour Insulin Receptor anticorps (Middle Region) (ABIN2776773)
Antigène
Voir toutes Insulin Receptor (INSR) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- EEVSGTKGRQ ERNDIALKTN GDQASCENEL LKFSFIRTSF DKILLRWEPY
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against Insr. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 1372 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Insulin Receptor (INSR)
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Autre désignation
- Insr
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Sujet
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This receptor binds insulin and has a tyrosine-protein kinase activity. When it is present in a hybrid receptor with IGF1R, binds IGF1.
Alias Symbols: 4932439J01Rik, CD220, D630014A15Rik, IR, IR-A, IR-B
Protein Interaction Partner: Arrb2, Src, Akt1, Jup, Irs1, Grb10, Snx9, Dok3, Sh2b2, Flot1, Dok1, Cav3, Socs1, Socs3, Sorbs1, Cav1, Pik3r1,
Protein Size: 1372 -
Poids moléculaire
- 155 kDa
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ID gène
- 16337
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NCBI Accession
- NM_010568, NP_034698
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UniProt
- P15208
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Pathways
- Signalisation NF-kappaB, Signalisation RTK, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
Antigène
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