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Insulin Receptor anticorps (Middle Region)

INSR Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Porc, Cobaye, Lapin WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2776774
  • Antigène Voir toutes Insulin Receptor (INSR) Anticorps
    Insulin Receptor (INSR)
    Épitope
    • 17
    • 16
    • 14
    • 12
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 174
    • 96
    • 80
    • 15
    • 14
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Porc, Cobaye, Lapin
    Hôte
    • 168
    • 27
    • 3
    • 1
    Lapin
    Clonalité
    • 160
    • 39
    Polyclonal
    Conjugué
    • 119
    • 17
    • 16
    • 8
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Insulin Receptor est non-conjugé
    Application
    • 144
    • 86
    • 55
    • 28
    • 18
    • 16
    • 15
    • 15
    • 13
    • 13
    • 8
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    ENNVVHLMWQ EPKEPNGLIV LYEVSYRRYG DEELHLCVSR KHFALERGCR
    Homologie
    Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against INSR. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human INSR
    Top Product
    Discover our top product INSR Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 1382 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    Insulin Receptor (INSR)
    Autre désignation
    INSR (INSR Produits)
    Synonymes
    anticorps CD220, anticorps HHF5, anticorps 4932439J01Rik, anticorps D630014A15Rik, anticorps IR, anticorps IR-A, anticorps IR-B, anticorps 18402, anticorps CG18402, anticorps DIHR, anticorps DILR, anticorps DIR, anticorps DIRH, anticorps DIRbeta, anticorps DInR, anticorps DInr, anticorps Dir-a, anticorps Dir-b, anticorps Dmel\\CG18402, anticorps INR, anticorps INS, anticorps Inr, anticorps Inr-alpha, anticorps Inr-beta, anticorps InsR, anticorps dINR, anticorps dIR, anticorps dIRH, anticorps dInR, anticorps dInr, anticorps dInsR, anticorps dinr, anticorps dir, anticorps er10, anticorps inr, anticorps insulin/insulin-like growth factor receptor, anticorps l(3)05545, anticorps l(3)93Dj, anticorps l(3)er10, anticorps lnR, anticorps ir-A, anticorps CTK-1, anticorps ir, anticorps INSR, anticorps NV14476, anticorps cd220, anticorps hhf5, anticorps insulin receptor, anticorps Insulin-like receptor, anticorps insulin receptor L homeolog, anticorps INSR, anticorps Insr, anticorps InR, anticorps LOC100122567, anticorps LOC100451802, anticorps insr.L
    Sujet
    This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. INSR mediates the metabolic functions of insulin. INSR binding to insulin stimulates association of the receptor with downstream media
    Alias Symbols: CD220, HHF5
    Protein Interaction Partner: KRT31, UBC, ARRB2, MOK, Grb2, Hgf, DOK1, SH2B1, Stat5b, TEAD1, STAT5A, JAK2, JAK1, IRS1, IRF7, PLCG1, GRB10, Socs6, Socs1, SOCS3, SH2B2, HGS, INPPL1, Calmodulin, Mad2l1, KRT27, DOK5, DOK4, SNX6, SNX4, SNX2, ACP1, PTPN2, SYNCRIP, FRS2, PIK3R3, VAV3, ARHGAP
    Protein Size: 1382
    Poids moléculaire
    154 kDa
    ID gène
    3643
    NCBI Accession
    NM_000208, NP_000199
    UniProt
    P06213
    Pathways
    Signalisation NF-kappaB, Signalisation RTK, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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