DDIT3 anticorps (N-Term)

N° du produit ABIN2777369

Cet anticorps Lapin Polyclonal détecte spécifiquement DDIT3 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Mouton, Lapin, Chien, Cobaye, Cheval et Chévre.

Aperçu rapide pour DDIT3 anticorps (N-Term) (ABIN2777369)

Antigène: DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Mouton, Lapin, Chien, Cobaye, Cheval, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDIT3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-DDIT3 anticorps

Épitope: N-Term

Séquence: SLPFSFGTLS SWELEAWYED LQEVLSSDEN GGTYVSPPGN EEEESKIFTT

Homologie: Cow: 86%, Dog: 86%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 92%, Sheep: 86%

Attributs du produit: This is a rabbit polyclonal antibody against DDIT3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human DDIT3

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DDIT3

Antigène: DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

Autre désignation: DDIT3

Sujet: This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
Protein Interaction Partner: CCDC153, ATPAF2, ZC3H14, TRIB3, C11orf30, BATF3, VPS37C, AMOTL2, HSD17B14, SNAPC5, HDAC5, HDAC6, TNFSF12, ZBTB25, UBC, LMO2, HDAC1, FOSL2, EP300, CEBPG, C14orf80, GIPC1, BATF, ATF4, PPIB, MAFF, CREB3, FOSL1, NFIL3, MAFG, JUNB, JUN, FOS, EPAS1, DDIT3, DBP,
Protein Size: 192

Poids moléculaire: 21 kDa

ID gène: 1649

NCBI Accession: NP_001181985

UniProt: F8VS99

Pathways: Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis