PIAS3 anticorps (Middle Region)

N° du produit ABIN2777575

Cet anticorps anti-PIAS3 est un anticorps Lapin Polyclonal détectant PIAS3 dans WB. Adapté pour Humain, Rat, Chien, Boeuf (Vache), Cheval, Cobaye et Lapin.

Aperçu rapide pour PIAS3 anticorps (Middle Region) (ABIN2777575)

Antigène: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Reactivité: Humain, Rat, Chien, Boeuf (Vache), Cheval, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIAS3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PIAS3 anticorps

Épitope: Middle Region

Séquence: DEIQFMEDGS WCPMKPKKEA SEVCPPPGYG LDGLQYSPVQ GGDPSENKKK

Homologie: Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Rabbit: 79%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against PIAS3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PIAS3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 628 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PIAS3

Antigène: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Autre désignation: PIAS3

Sujet: PIAS3 is a member of the protein inhibitor of activated STAT (PIAS) family. It also activates TGF-beta/SMAD transcriptional responses. This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ14651, ZMIZ5
Protein Interaction Partner: UBC, HIC1, TRIM63, TRIM55, TAB2, SUMO1, CBS, SUMO2, SUMO3, STAT3, NCOA2, CREM, PRPF40A, SERPINA10, GEMIN4, UBE2I, SKIL, HNRNPK, ZFHX3, SERBP1, SATB1, ERBB4, Bcl11a, ELAVL1, PPP1CA, Grm7, Grm8, Grm6, Grm4, TRIM8, RAC1, C19orf60, CARHSP1, UBA1, PSMC1, TRIM2
Protein Size: 628

Poids moléculaire: 68 kDa

ID gène: 10401

NCBI Accession: NM_006099, NP_006090

UniProt: Q9Y6X2

Pathways: Signalistation JAK/STAT