PTGER3 anticorps (Middle Region)

N° du produit ABIN2778262

Détail du produit anti-PTGER3 anticorps

Antigène: PTGER3 (Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTGER3 est non-conjugé

Application: Western Blotting (WB)

Séquence: STVIDPSRFC AQPFRWFLDL SFPAMSSSHP QLPLTLASFK LLREPCSVQL

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PTGER3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PTGER3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 425 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PTGER3

Antigène: PTGER3 (Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3))

Autre désignation: PTGER3 (PTGER3 Produits)

Synonymes: anticorps PTGER3, anticorps EP3, anticorps EP3-I, anticorps EP3-II, anticorps EP3-III, anticorps EP3-IV, anticorps EP3e, anticorps PGE2-R, anticorps PTGEREP3, anticorps Rep3, anticorps rEP3a, anticorps rEP3b, anticorps Pgerep3, anticorps Ptgerep3, anticorps prostaglandin E receptor 3, anticorps prostaglandin E receptor 3 L homeolog, anticorps prostaglandin E receptor 3 (subtype EP3), anticorps PTGER3, anticorps ptger3.L, anticorps Ptger3

Sujet: PTGER3 is the receptor for prostaglandin E2 (PGE2), the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems.The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple alternatively spliced transcript variants encoding eight distinct isoforms have been reported.
Alias Symbols: EP3, EP3-I, EP3-II, EP3-III, EP3-IV, EP3e, MGC141828, MGC141829, MGC27302, PGE2-R
Protein Interaction Partner: NOTCH2NL, INCA1, KRTAP10-3, KRTAP10-8, KRTAP10-9, KRTAP10-7, TRIM42, MGAT5B, KRT40, CCDC33, ADAMTSL4, EFEMP2, RGS17, SPRY2, KRT38, RGS20, TCF4, REL, MEOX2, KRT31, CDA, GHRL, MKLN1, PTGER1,
Protein Size: 425

Poids moléculaire: 47 kDa

ID gène: 5733

NCBI Accession: NM_000957, NP_000948