PPARA anticorps (Middle Region)

N° du produit ABIN182928

Cet anticorps anti-PPARA est un anticorps Lapin Polyclonal détectant PPARA dans WB. Adapté pour Humain, Souris, Rat, Chien, Cheval, Porc, Chévre, Cobaye, Lapin et Mouton.

Aperçu rapide pour PPARA anticorps (Middle Region) (ABIN182928)

Antigène: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Porc, Chévre, Cobaye, Lapin, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPARA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PPARA anticorps

Épitope: Middle Region

Séquence: IYEAYLKNFN MNKVKARVIL SGKASNNPPF VIHDMETLCM AEKTLVAKLV

Homologie: Dog: 92%, Goat: 91%, Guinea Pig: 77%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 85%, Rat: 85%, Sheep: 91%

Attributs du produit: This is a rabbit polyclonal antibody against PPARA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PPARA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 468 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PPARA

Antigène: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Autre désignation: PPARA

Sujet: Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals which contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor.
Alias Symbols: PPAR, NR1C1, hPPAR, PPARalpha
Protein Interaction Partner: SIRT1, PRMT1, PRMT8, RXRA, CHD9, NCOA1, FOXA3, CDK3, TNP1, HSP90AA1, NCOR2, NCOR1, SUMO1, UBE2I, LPIN1, SRC, TRA, MECR, STAC3, HELZ2, NRBF2, AIP, NR1H3, MED24, GADD45G, GADD45B, AKAP13, PPARGC1A, MED1, EP300, NRIP1, DAP3, MAPK3, DUT, RXRG, PRKCD, PRKCA, M
Protein Size: 468

Poids moléculaire: 51 kDa

ID gène: 5465

NCBI Accession: NM_005036, NP_005027

UniProt: Q07869

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C