ATF2 anticorps (C-Term)

N° du produit ABIN2778291

Cet anticorps Lapin Polyclonal détecte spécifiquement ATF2 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cheval et Cobaye.

Aperçu rapide pour ATF2 anticorps (C-Term) (ABIN2778291)

Antigène: ATF2 (Activating Transcription Factor 2 (ATF2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATF2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ATF2 anticorps

Épitope: C-Term

Séquence: LRNEVAQLKQ LLLAHKDCPV TAMQKKSGYH TADKDDSSED ISVPSSPHTE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ATF2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ATF2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 505 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ATF2

Antigène: ATF2 (Activating Transcription Factor 2 (ATF2))

Autre désignation: ATF2

Sujet: ATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.
Alias Symbols: HB16, CREB2, TREB7, CRE-BP1
Protein Interaction Partner: MAPK10, MAPK9, MAPK8, MAPK1, SUMO1, KIFC3, FOS, MAPK14, EXOSC8, JUN, CREBBP, ATF2, CEBPG, BACH1, ATF4, ATF3, BATF3, DDIT3, BATF, FOSL1, H2AFY, RB1, GAPDH, NME2P1, TUBB, SFXN1, RAB2B, TMX1, GRPEL1, COLGALT1, AHNAK, SQRDL, RTN4, APMAP, C19orf10, RAB14, ERO1
Protein Size: 505

Poids moléculaire: 55 kDa

ID gène: 1386

NCBI Accession: NM_001880, NP_001871

Pathways: Signalisation MAPK, Signalisation RTK, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades