Crk anticorps (C-Term)

N° du produit ABIN2779332

Détail du produit anti-Crk anticorps

Antigène: Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Crk est non-conjugé

Application: Western Blotting (WB)

Séquence: IPVPYVEKYR PASASVSALI GGNQEGSHPQ PLGGPEPGPY AQPSVNTPLP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CRK. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 304 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Crk

Antigène: Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

Autre désignation: CRK (CRK Produits)

Synonymes: anticorps CG1587, anticorps CRK, anticorps D-CRK, anticorps D-Crk, anticorps DCrk, anticorps Dcrk, anticorps Dmel\\CG1587, anticorps crk, anticorps dCRK, anticorps dCrk, anticorps fb34h10, anticorps fc05a01, anticorps fi19g05, anticorps wu:fb34h10, anticorps wu:fc05a01, anticorps wu:fc54a04, anticorps wu:fi19g05, anticorps zgc:100936, anticorps CRKII, anticorps p38, anticorps Crko, anticorps crk2, anticorps crkII, anticorps v-crk, anticorps P38C-CRK, anticorps Crk-I, anticorps Crk-II, anticorps Crk-III, anticorps Crk3, anticorps CrkIII, anticorps c-Crk, anticorps Crk oncogene, anticorps v-crk avian sarcoma virus CT10 oncogene homolog, anticorps CRK proto-oncogene, adaptor protein, anticorps v-crk avian sarcoma virus CT10 oncogene homolog L homeolog, anticorps v-crk sarcoma virus CT10 oncogene homolog, anticorps Crk, anticorps crk, anticorps CRK, anticorps crk.L

Sujet: This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
Alias Symbols: CRKII, p38
Protein Interaction Partner: FAM154A, HUWE1, ABL2, ABL1, SPRR2A, MET, CBL, BAG3, LMNA, ERBB3, ERBB2, EGFR, PPFIBP2, ATXN1, PTPN4, MAPK4, DOK1, BCAR1, NANS, FUBP1, SPR, HSPB1, DHX9, SERPINH1, ATIC, PIK3R2, PIK3R1, PIK3CD, PIK3CB, PIK3CA, PIK3C2B, SERPINB6, LYZ, KRT19, KRT17, KRT16, KR
Protein Size: 304

Poids moléculaire: 34 kDa

ID gène: 1398

NCBI Accession: NM_016823, NP_058431

UniProt: P46108

Pathways: Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor