TNFSF15 anticorps (C-Term)

N° du produit ABIN2779354

Détail du produit anti-TNFSF15 anticorps

Antigène: TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Épitope: C-Term

Reactivité: Humain, Souris, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFSF15 est non-conjugé

Application: Western Blotting (WB)

Séquence: CSEIRQAGRP NKPDSITVVI TKVTDSYPEP TQLLMGTKSV CEVGSNWFQP

Homologie: Cow: 79%, Human: 100%, Mouse: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TNFSF15. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TNFSF15

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TNFSF15

Antigène: TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Autre désignation: TNFSF15 (TNFSF15 Produits)

Synonymes: anticorps TTPAL, anticorps TL1, anticorps TL1A, anticorps VEGI, anticorps VEGI192A, anticorps Tl1, anticorps Tl1a, anticorps Vegi, anticorps tumor necrosis factor superfamily member 15, anticorps TNF superfamily member 15, anticorps tumor necrosis factor (ligand) superfamily, member 15, anticorps TNFSF15, anticorps Tnfsf15

Sujet: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: TNFRSF25, TNFRSF6B,
Protein Size: 192

Poids moléculaire: 21 kDa

ID gène: 9966

Pathways: Positive Regulation of Endopeptidase Activity, Autophagy