FASL anticorps (Middle Region)
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- Antigène Voir toutes FASL Anticorps
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
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Épitope
- Middle Region
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Reactivité
- Humain, Porc, Boeuf (Vache), Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FASL est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MHTASSLEKQ IGHPSPPPEK KELRKVAHLT GKSNSRSMPL EWEDTYGIVL
- Homologie
- Cow: 86%, Horse: 79%, Human: 100%, Pig: 93%, Rabbit: 90%
- Attributs du produit
- This is a rabbit polyclonal antibody against FASLG. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product FASL Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 281 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
- Autre désignation
- FASLG (FASL Produits)
- Synonymes
- anticorps ALPS1B, anticorps APT1LG1, anticorps APTL, anticorps CD178, anticorps CD95-L, anticorps CD95L, anticorps FASL, anticorps TNFSF6, anticorps fasl, anticorps Fas-L, anticorps Faslg, anticorps Tnfsf6, anticorps gld, anticorps Apt1Lg1, anticorps Fasl, anticorps FASLG, anticorps zgc:162027, anticorps Fas ligand, anticorps Fas ligand L homeolog, anticorps Fas ligand (TNF superfamily, member 6), anticorps FASLG, anticorps faslg.L, anticorps Fasl, anticorps Faslg, anticorps faslg
- Sujet
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TNFSF6 is a cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T cell mediated apoptosis and in T cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.
Alias Symbols: APT1LG1, CD178, CD95L, FASL, TNFSF6, CD95-L
Protein Interaction Partner: RGS20, TRIP6, NOTCH2NL, KRT40, FAS, CFLAR, FADD, CASP8, NCF1, MACC1, SH3PXD2B, SNX33, SH3RF2, RIMBP3C, SNX18, EPS8L3, ARHGAP9, SAMSN1, MPP4, SRGAP1, BAIAP2L1, NCKIPSD, SNX9, MYO15A, ITSN2, TJP3, OSTF1, SRGAP2, DNMBP, SORBS3, SRGAP3, DOCK4, SH3PXD2A, KALRN
Protein Size: 281 - Poids moléculaire
- 31 kDa
- ID gène
- 356
- NCBI Accession
- NM_000639, NP_000630
- UniProt
- P48023
- Pathways
- Apoptose, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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