Serotonin Receptor 2B anticorps (N-Term)
Aperçu rapide pour Serotonin Receptor 2B anticorps (N-Term) (ABIN2779377)
Antigène
Voir toutes Serotonin Receptor 2B (HTR2B) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- HTR2B Antibody - N-terminal region
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Séquence
- QTESIPEEMK QIVEEQGNKL HWAALLILMV IIPTIGGNTL VILAVSLEKK
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Homologie
- Cow: 100%, Dog: 80%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Pig: 87%
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Attributs du produit
- This is a rabbit polyclonal antibody against HTR2B. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human HTR2B
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30716-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Serotonin Receptor 2B (HTR2B)
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Autre désignation
- HTR2B
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Sujet
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Background Information: Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets, central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.
Gene Name: 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
Alternative Symbols: 5-HT2B, 5-HT-2B, 5-HT(2B)
Protein Name: 5-hydroxytryptamine receptor 2B
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Poids moléculaire
- 54 kDa
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ID gène
- 3357
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NCBI Accession
- NP_000858
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UniProt
- P41595
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Pathways
- Signalistation JAK/STAT, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
Antigène
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